Acupressure for Pain of Osteoarthritis : A Systematic Review


  • Srinalesti Mahanani Department of Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Nyoman Kertia Department of Internal Medicine, Dr. Sardjito Hospital, Yogyakarta, Indonesia
  • Ema Madyaningrum Department of Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Wiwin Lismidiati Department of Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia



acupressure, complementary therapy, osteoarthritis, pain


Background: Osteoarthritis can be defined as a disorder of movable joints characterized by deterioration of articular cartilage; osteophyte formation and bone remodeling; changes in periarticular tissues; and a low-grade, nonpurulent inflammation of variable degree. Acupressure is a traditional non-pharmacological intervention that promotes blood circulation and muscle activity.

Purpose: This review aimed to investigate the efficacy of acupressure as a complementary therapy method for the pain of osteoarthritis.

Methods: Four electronic databases were searched from PubMed, ProQuest, Scopus, and The Cochrane Library use PICO strategy. In studies comparing acupressure with sham acupuncture, no intervention, or conventional intervention was eligible for inclusion. Article study is published on 2012-2022, using English and design RCT and Quasi-experiment. Prisma analysis was used in selection process. The risk of bias in the included studies was assessed using the Joanna Briggs Institute Critical Appraisal Tools for Quasi-Experimental Studies and Randomized Controlled Trials.

Results: There were 12 reports selected for review with the homogeny of knee Osteoarthritis. Outcomes were either objectively- or subjectively assessed improvements in specific pain parameters and safety for clinical use. Results showed more clinical trials with proper methodology are needed to confirm the effectiveness of acupressure for the pain of Osteoarthritis. The results of the review showed a positive effect in reducing pain level with acupressure intervention as either the main or complementary therapy.

Conclusion: This systematic review shows that acupressure as a single or complementary intervention provides significant benefits in the management of Osteoarthritis. Further trials with a more rigorous design are needed to further validate and address the limitations of the current evidence.


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Akbarnezhad, N. et al. (2019). ‘The effect of acupressure therapy on pain, stiffness and physical functioning of knees among older adults diagnosed with osteoarthritis: A pilot randomized control trial’, European Journal of Integrative Medicine, 28, pp. 68–75. doi: 10.1016/j.eujim.2019.04.007.

Alinaghizadeh, M. et al. (2021). ‘Effect of Persian acupressure (Ghamz) on patients with knee osteoarthritis: A single-blinded parallel clinical trial’, Pain Manag. Nurs., 22(6), pp. 820–827. doi: 10.1016/j.pmn.2021.06.002.

Chatawatee, B. et al. (2022). ‘Effectiveness of knee acupressure along with herbal knee poultice for knee osteoarthritis treatment: A pilot pre-post clinical study’, Journal of Herbal Medicine, 32. doi: 10.1016/j.hermed.2021.100498.

Cheung, D. S. T. et al. (2020). ‘Self-administered acupressure for knee osteoarthritis in middle-aged and older adults: a pilot randomized controlled trial’, Acupunct. Med., 38(2), pp. 75–85. doi: 10.1177/0964528419883269.

Guo, D. et al. (2022). ‘Self-administered acupressure and exercise for patients with osteoarthritis: A randomized controlled trial’, Clin. Rehabil., 36(3), pp. 350–358. doi: 10.1177/02692155211049155.

Horng, H.-C. et al. (2013). ‘The effects of collateral meridian therapy for knee osteoarthritis pain management: A pilot study’, Journal of Manipulative and Physiological Therapeutics, 36(1), pp. 51–56. doi: 10.1016/j.jmpt.2012.12.003.

Jang, M., Lim, Y.-M. and Park, H. (2019). ‘Effects of auricular acupressure on joint pain, range of motion, and sleep in the elderly with knee osteoarthritis ’, Journal of Korean Academy of Community Health Nursing, 30(1), pp. 79–89. doi: 10.12799/jkachn.2019.30.1.79.

Li, L. W. et al. (2018). ‘Self-Acupressure for Older Adults With Symptomatic Knee Osteoarthritis: A Randomized Controlled Trial’, Arthritis Care & Research, 70(2), pp. 221–229. doi:

Mahanani, S. and Idris, D. N. T. (2020). Buku ajar keperawatan paliatif?: asuhan keperawatan pasien kusta berfokus pada aspek psikologi dan sosial. Kediri: CV. Adjie Media Nusantara.

Mahanani, S. and Yusiana, M. A. (2020). Terapi Imajinasi Terbimbing. Nganjuk: CV Adjie Media Nusantara.

Moher, D. et al. (2009). ‘Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.’, BMJ (Clinical research ed.), 339, p. b2535. doi: 10.1136/bmj.b2535.

Rani, M. et al. (2020). ‘Acupressure as an Adjunct to Pharmacological Treatment for Depression, Anxiety, and Stress in Patients with Knee Osteoarthritis.’, Journal of acupuncture and meridian studies, 13(4), pp. 129–135. doi: 10.1016/j.jams.2020.07.001.

Rani, M., Sharma, L. and Advani, U. (2022). ‘Acupressure combined with pharmacological treatment in patients with osteoarthritis of the knee: a randomized trial’, Advances in Integrative Medicine, 9(1), pp. 30–36. doi: 10.1016/j.aimed.2021.09.001.

Shu, Z. et al. (2021). ‘2021 Integrative Medicine & Health Symposium Abstracts’, Global Advances in Health and Medicine, 10, p. 21649561211003690. doi: 10.1177/21649561211003689.

Sorour, A. S., Ayoub, A. S. and Abd El Aziz, E. M. (2014). ‘Effectiveness of acupressure versus isometric exercise on pain, stiffness, and physical function in knee osteoarthritis female patients’, Journal of Advanced Research, 5(2), pp. 193–200. doi: 10.1016/j.jare.2013.02.003.

Sun, K. et al. (2019). ‘Is traditional Chinese medicine use associated with worse patient-reported outcomes among Chinese american rheumatology patients?’, Journal of Rheumatology, 46(12), pp. 1634–1639. doi: 10.3899/jrheum.181148.




How to Cite

Mahanani, S., Kertia, N., Madyaningrum, E., & Lismidiati, W. (2023). Acupressure for Pain of Osteoarthritis : A Systematic Review. Journal Of Nursing Practice, 7(1), 191–208.