Factors Influencing Pre-Hospital Delay in Acute Coronary Syndrome Patients
DOI:
https://doi.org/10.30994/jnp.v9i3.1038Keywords:
Acute Coronary Syndrome, Emergency Department, Pre-hospital DelayAbstract
Background: Acute Coronary Syndrome (ACS) is a major cause of morbidity and mortality worldwide, with delayed hospital presentation contributing to poor outcomes. Pre-hospital delay, defined as the time from symptom onset to seeking definitive care, is influenced by patient, symptom, and system-related factors. Evidence from Indonesia on determinants of such delays remains limited.
Purpose: This study aimed to analyze factors associated with pre-hospital delay among ACS patients in the Emergency Department of Dr. Wahidin Sudiro Husodo Regional Hospital, Mojokerto City.
Methods: An observational, analytic, cross-sectional study was conducted in 2024, with 70 adult ACS patients recruited through consecutive sampling. Data were collected via standardized questionnaires and medical record review, including demographic, clinical, transportation, attack type, symptom onset timing, health insurance, and ACS knowledge. Bivariate and multivariate logistic regression analyses were performed to identify predictors of pre-hospital delay.
Results: The mean age of respondents was 61.67 years, with 60% male and 61.4% lacking knowledge of ACS. Most arrived by private vehicle (87.1%) and experienced a new attack (77.1%). Pre-hospital delay occurred in 77.1% of respondents. Multivariate analysis showed that the type of attack had the highest odds ratio (OR = 5.55) for pre-hospital delay, although not statistically significant (p = 0.115). Transportation, time of onset, and ACS knowledge did not demonstrate significant associations but suggested potential confounding effects.
Conclusion: Pre-hospital delay is highly prevalent among ACS patients in this setting. No significant predictors were identified, suggesting delays reflect complex behavioral and system factors. Given the limited sample size, the findings should be interpreted with caution. Improving public awareness and emergency access remains essential.
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AL Ahmadi, A. F., AL Saedi, M. F., Alahmadi, A. E., Alharbi, M. G., Alharbi, I. H., & Radman Al-Dubai, S. A. (2020). Pre-Hospital Delay Among Patients with Acute Myocardial Infarction in Saudi Arabia. Saudi Medical Journal, 41(8), 819–827. https://doi.org/10.15537/SMJ.2020.8.25185.
Ananchaisarp, T., Tantarattanapong, S., Satayukun, S., Thepuatrakul, K., Techapattanakorn, N., Limwattanalert, N., Mettraiyasakul, N., Rattanakitkoson, S., & Chuaboon, A. (2023). Delayed Pre-hospital Time in Acute Coronary Syndrome Patients and Associated Factors in a Hospital in Southern Thailand. Journal of Health Research, 37(2), 89–96. https://doi.org/10.56808/2586-940X.1004.
Anggraini, N. A., Said, F., Umar, N. S., & Ambarika, R. (2023). Importance of Acute Coronary Syndrome Knowledge to Improve Early Detection and Reduce Prehospital Delay in Patient with Acute Coronary Syndrome: A Systematic Review. Open Access Macedonian Journal of Medical Sciences, 11(G), 33–42. https://doi.org/10.3889/oamjms.2023.10623.
Bauer, D., Neuberg, M., Nováčková, M., Kočka, V., & Toušek, P. (2023). Pre-hospital delay, clinical characteristics, angiographic findings, and in-hospital mortality in young and middle-aged adults with acute coronary syndrome: a single-centre registry analysis. European Heart Journal, Supplement, 25(Se), E33–E39. https://doi.org/10.1093/eurheartjsupp/suad102.
Caltabellotta, T., Magne, J., Salerno, B., Pradel, V., Petitcolin, P. B., Auzemery, G., Virot, P., & Aboyans, V. (2021). Characteristics associated with patient delay during the management of ST-segment elevated myocardial infarction, and the influence of awareness campaigns. In Archives of Cardiovascular Diseases (Vol. 114, Issue 4). https://doi.org/10.1016/j.acvd.2020.09.004.
Chowdhury, I. Z., Amin, M. N., Chowdhury, M. Z., Rahman, S. M., Ahmed, M., & Cader, F. A. (2021). Pre hospital delay and its associated factors in acute myocardial infarction in a developing country. PloS One, 16(11), e0259979. https://doi.org/10.1371/journal.pone.0259979.
Eckle, V. S., Lehmann, S., & Drexler, B. (2021). Prehospital management of patients with suspected acute coronary syndrome: Real world experience reflecting current guidelines. Medizinische Klinik - Intensivmedizin Und Notfallmedizin, 116(8), 694–697. https://doi.org/10.1007/s00063-020-00739-3.
Hu, D. Q., Hao, Y. C., Liu, J., Yang, N., Yang, Y. Q., Sun, Z. Q., Zhao, D., & Liu, J. (2022). Pre-hospital delay in patients with acute myocardial infarction in China: findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome (CCC-ACS) project. Journal of Geriatric Cardiology, 19(4), 276–283. https://doi.org/10.11909/j.issn.1671-5411.2022.04.005.
Jaskiewicz, F., & Zielinska, M. (2019). Prehospital clinical presentation in patients with acute coronary syndrome complicated by cardiogenic shock: A single center study. Australian Critical Care, 32(4), 293–298. https://doi.org/10.1016/j.aucc.2018.08.002.
Khaled, M. F. I., Adhikary, D. K., Islam, M. M., Alam, M. M., Rahman, M. W., Chowdhury, M. S. I. T., Perveen, R., Ahmed, S., Ashab, E., Shakil, S. S., Ansari, S., Das, B. C., Mohammad, N., Ehsan, M. A., Jamil, A. B. M., Mostafa, Z., Abedin, Z., & Banerjee, S. K. (2022). Factors Responsible for Prehospital Delay in Patients with Acute Coronary Syndrome in Bangladesh. Medicina (Lithuania), 58(9), 1–11. https://doi.org/10.3390/medicina58091206.
Kontsevaya, A. V., Kononets, E. N., & Goryachkin, E. A. (2019). Delayed help-seeking for emergency medical care of patients with acute coronary syndrome/myocardial infarction: Review of studies. Russian Journal of Cardiology, 24(8), 132–139. https://doi.org/10.15829/1560-4071-2019-8-132-139.
Mirzaei, S., Steffen, A., Vuckovic, K., Ryan, C., Bronas, U. G., Zegre-hemsey, J., & Devon, H. A. (2020). The association between symptom onset characteristics and prehospital delay in women and men with acute coronary syndrome. European Journal of Cardiovascular Nursing, 19(2), 142–154. https://doi.org/10.1177/1474515119871734.
Mujtaba, S. F., Sohail, H., Ram, J., Waqas, M., Hassan, M., Sial, J. A., Naseeb, K., Saghir, T., & Karim, M. (2021). Pre-hospital Delay and Its Reasons in Patients With Acute Myocardial Infarction Presenting to a Primary Percutaneous Coronary Intervention-Capable Center. Cureus, 13(1), 1–8. https://doi.org/10.7759/cureus.12964.
Ogushi, A., Hikoso, S., Kitamura, T., Nakatani, D., Mizuno, H., Suna, S., Okada, K., Dohi, T., Sotomi, Y., Kida, H., Sunaga, A., Oeun, B., Sato, T., Sakata, Y., Sato, H., Hori, M., Komuro, I., Iso, H., & Sakata, Y. (2022). Factors Associated With Prehospital Delay Among Patients With Acute Myocardial Infarction in the Era of Percutaneous Coronary Intervention-Insights From the OACIS Registry. Circulation Journal, 86(4), 600–608. https://doi.org/10.1253/circj.CJ-21-0777.
Petrova, D., Garrido, D., Blakoe, M., & Garcia-retamero, R. (2024). Social Science & Medicine Anticipated prehospital decision delay in response to different symptom clusters in acute coronary syndrome : Results from the Spanish Cardiobarometer study e Antonio Ramírez-Hern a e S a. Social Science and Medicine, 359. https://doi.org/10.1016/j.socscimed.2024.117263.
Rosjidi, C. H. (2020). Early Home Care Errors and the Impact on Delay in Hospital for Patients with Coronary Heart Disease. Jurnal Keperawatan, 11(1), 1–9. https://doi.org/10.22219/jk.v11i1.9752.
Sundermeyer, J., Schock, A., Kellner, C., Haller, P. M., Lehmacher, J., Thießen, N., Toprak, B., Scharlemann, L., Twerenbold, R., & Sörensen, N. A. (2025). Pre ‑ hospital admission of heparin in patients with suspected non ‑ ST segment elevation acute coronary syndrome. Clinical Research in Cardiology, 114(6), 738–748. https://doi.org/10.1007/s00392-024-02507-1.
WHO. (2023). World health statistics 2023: Monitoring health for the SDGs, sustainable development goals. https://www.who.int/publications/i/item/9789240074326.
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